Always inform your doctor about all medications you are taking, including over-the-counter drugs and supplements, before starting Amiloride HCTZ 5/50 mg. Certain combinations can lead to adverse effects.
Amiloride HCTZ can interact significantly with:
| Potassium-sparing diuretics | Spironolactone, Triamterene | Increased risk of hyperkalemia (high potassium levels). Careful monitoring is required. |
| NSAIDs | Ibuprofen, Naproxen | Reduced effectiveness of Amiloride HCTZ. Increased risk of kidney problems. |
| Lithium | Lithium carbonate | Increased lithium levels, potentially leading to lithium toxicity. Close monitoring is necessary. |
| ACE inhibitors | Lisinopril, Ramipril | Increased risk of hyperkalemia. Regular potassium level checks are recommended. |
| Digoxin | Digoxin | Increased risk of digoxin toxicity. Monitor digoxin levels closely. |
Contraindications for Amiloride HCTZ 5/50 mg include:
- Severe kidney disease Anuria (absence of urine production) Hyperkalemia (high potassium levels) Severe hepatic impairment Known allergy to amiloride or hydrochlorothiazide or any sulfonamide-derived drug
This information is not exhaustive. Consult your physician or pharmacist for a complete list of potential drug interactions and contraindications specific to your health condition and other medications you are using. They can provide tailored advice and ensure safe medication use.
