Always inform your doctor about all medications you are currently taking, including over-the-counter drugs, herbal remedies, and supplements. This includes nitrates, commonly found in medications for chest pain (angina). Combining Apcalis SX with nitrates can cause a dangerous drop in blood pressure.
Alpha-blockers, used to treat high blood pressure or enlarged prostate, may also interact with Apcalis SX, potentially leading to significantly low blood pressure. Discuss this possibility with your physician before using both medications simultaneously.
Certain antifungals, like ketoconazole and itraconazole, can increase Apcalis SX levels in your blood, potentially intensifying its effects and increasing the risk of side effects. Your doctor may need to adjust your dosage of Apcalis SX or the antifungal.
Grapefruit juice can also interact with Apcalis SX. Avoid consuming grapefruit or grapefruit juice while taking this medication, as it can increase Apcalis SX’s concentration in your bloodstream.
Consult your doctor or pharmacist if you have any concerns about potential drug interactions before taking Apcalis SX, especially if you have pre-existing health conditions or are taking other medications. They can provide personalized advice and ensure your safety.


