Administer Azithromycin 500 mg IV as a slow intravenous infusion over at least 60 minutes to minimize the risk of local thrombophlebitis. Dilute the medication in 100 mL of compatible intravenous solution, such as 5% dextrose in water or 0.9% sodium chloride.
Monitor patients closely for adverse reactions, including arrhythmias, especially in patients with a history of cardiac conditions. Observe for hypersensitivity reactions such as rash, urticaria, or angioedema. Early detection allows for prompt intervention.
Note: Azithromycin’s IV formulation is primarily reserved for patients unable to tolerate oral administration due to severe nausea, vomiting, or malabsorption. Always refer to the current prescribing information for complete details regarding dosage, administration, and contraindications. Before administering, confirm patient allergies and review their complete medical history, including liver and kidney function.
Contraindications: Avoid Azithromycin in patients with known hypersensitivity to azithromycin or other macrolides. Exercise caution in patients with hepatic or renal impairment, adjusting the dosage as clinically indicated, guided by specific guidelines and medical professional recommendations. Close monitoring is required.
