Amoxicillin, clarithromycin, and lansoprazole are frequently prescribed together to eradicate Helicobacter pylori (H. pylori) infection, a bacterium commonly causing peptic ulcers and gastritis.
This triple therapy is particularly effective because each medication targets a different aspect of the infection:
- Amoxicillin: A penicillin-based antibiotic directly killing H. pylori bacteria. Clarithromycin: A macrolide antibiotic also effective against H. pylori, working synergistically with amoxicillin. Lansoprazole: A proton pump inhibitor (PPI) that reduces stomach acid production, creating a more favorable environment for the antibiotics to work and promoting ulcer healing.
Successfully eradicating H. pylori significantly reduces the risk of:
Recurrence of peptic ulcers. Development of stomach cancer. Gastritis complications.
While primarily used for H. pylori eradication, doctors may consider this combination in specific cases involving other gastric infections requiring broad-spectrum antibiotic coverage and acid suppression. Always consult your doctor for accurate diagnosis and tailored treatment.


