Intravenous azithromycin offers faster absorption than the oral form, leading to quicker onset of therapeutic effects. This is particularly beneficial in severely ill patients requiring immediate treatment. Peak plasma concentrations are significantly higher with IV administration.
Bioavailability and Absorption
Oral azithromycin’s bioavailability can vary due to food intake and gastric pH. IV administration bypasses this variability, ensuring consistent drug delivery. For patients with gastrointestinal issues hindering oral absorption, IV azithromycin provides a reliable alternative.
Patient Considerations
IV azithromycin requires a healthcare professional’s administration, unlike oral medication. This necessitates a hospital or clinic visit, potentially increasing costs and inconvenience. However, the rapid onset and predictable absorption profile outweigh this for patients needing prompt, reliable treatment.