Avoid taking amoxicillin concurrently with certain medications to prevent potentially harmful interactions. This is especially important for medications that affect kidney function or alter how your body processes drugs.
Medications Affecting Kidney Function
Amoxicillin is primarily eliminated by the kidneys. Combining it with medications that impair kidney function, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, increases the risk of amoxicillin accumulating in your body, potentially leading to side effects.
Medications Affecting Drug Metabolism
Some medications interfere with the liver’s ability to process amoxicillin. This can affect how effectively the antibiotic works or increase the likelihood of side effects. Examples include certain anticoagulants like warfarin. Always inform your doctor about all medications you’re taking, including over-the-counter drugs and supplements.
Specific Medication Interactions:
| NSAIDs | Ibuprofen, Naproxen | Increased risk of kidney damage and amoxicillin accumulation |
| Anticoagulants | Warfarin | Increased bleeding risk |
| Oral contraceptives | Various brands | Reduced effectiveness of birth control |
| Methotrexate | Methotrexate | Increased risk of methotrexate toxicity |
Always Consult Your Doctor
This information is not exhaustive. Before starting amoxicillin or any other medication, discuss potential interactions with your doctor or pharmacist. They can assess your individual health situation and provide personalized advice to ensure your safety and the effectiveness of your treatment.
