Avoid taking doxycycline with dairy products, antacids containing calcium, magnesium, or aluminum, or iron supplements. These substances can reduce doxycycline absorption, making the medication less effective.
Medications to Avoid
Doxycycline interacts negatively with certain medications. Concurrent use with warfarin (a blood thinner) may increase bleeding risk. Combining it with methotrexate can boost methotrexate’s toxicity. Simultaneous use with isotretinoin might elevate the risk of intracranial hypertension. Always inform your doctor of all medications, including over-the-counter drugs and supplements, you are taking before starting doxycycline.
Other Substances to Consider
Be cautious when consuming alcohol while on doxycycline. Excessive alcohol intake can increase the risk of side effects, such as nausea and stomach upset. Also, avoid sun exposure and use sunscreen with a high SPF. Doxycycline can increase your skin’s sensitivity to sunlight, potentially leading to sunburn.
Consult Your Physician
This information is not exhaustive. A thorough discussion with your doctor or pharmacist is crucial to determine potential interactions specific to your individual health circumstances and medication regimen. Never self-treat or alter your medication without professional medical guidance.


