Begin labetalol infusion at 2 mg/min. Monitor blood pressure closely every 5 minutes.
Increase the infusion rate by 2 mg/min increments every 10-15 minutes, as needed, to achieve target blood pressure. The maximum rate is usually 8 mg/min; however, adjust based on individual patient response and tolerance. Continuous blood pressure monitoring is critical.
Target systolic blood pressure reduction should be gradual, aiming for approximately 20-25% decrease within 2-6 hours. Adjust titration speed accordingly. Closely observe for adverse effects, including bradycardia, hypotension, and heart block. Reduce the infusion rate if side effects occur.
Remember: This protocol serves as a guideline. Individual patient needs vary significantly. Always tailor the titration to the specific clinical presentation and patient response. Consult relevant clinical guidelines and maintain close communication with the medical team for optimal patient care. Dosage adjustments must be made based on continuous monitoring and clinical judgment.
