Closely monitor blood pressure every 5 minutes initially, then adjust frequency based on patient response and stability. Target a gradual reduction in blood pressure, avoiding precipitous drops.
Continuously assess heart rate and rhythm. Bradycardia is a potential adverse effect; be prepared to administer atropine if necessary. Regular ECG monitoring is recommended, especially in patients with pre-existing cardiac conditions.
Observe for signs of hypotension, including dizziness, lightheadedness, and syncope. Position the patient supine or semi-recumbent to minimize orthostatic effects. Fluid resuscitation may be required.
Monitor respiratory rate and depth. While rare, respiratory depression is possible. Be prepared to provide ventilatory support if needed.
Assess for signs of bronchospasm, particularly in patients with asthma or COPD. Have bronchodilators readily available. Observe for wheezing or increased respiratory effort.
Pay close attention to the patient’s level of consciousness and mental status. Report any changes immediately. Assess for neurological symptoms.
Document all vital signs, medications administered, and any observed adverse events. Regularly review the patient’s medical history for contraindications and potential drug interactions.


