Potential Drug Interactions and Precautions

Always inform your doctor about all medications you’re taking, including over-the-counter drugs, supplements, and herbal remedies. Cephalexin can interact with certain medications. For example, probenecid reduces cephalexin excretion, potentially leading to higher blood levels and increased risk of side effects. Concurrent use with anticoagulants like warfarin may increase bleeding risk; careful monitoring is necessary.

Kidney problems significantly impact cephalexin elimination. Your doctor will adjust your dosage if you have reduced kidney function. Similarly, liver disease may affect how your body processes the drug, requiring dosage modifications. Be sure to discuss any existing liver or kidney conditions.

Allergic reactions are possible. Prior antibiotic allergies, especially to penicillin, increase the risk. Watch for symptoms like rash, hives, swelling, or difficulty breathing; seek immediate medical attention if these occur. Cephalexin can also cause gastrointestinal upset; taking it with food may help.

While generally safe during pregnancy and breastfeeding, discuss cephalexin use with your doctor to weigh the benefits against potential risks to the infant. Finally, alcohol consumption while on cephalexin isn’t specifically contraindicated, but excessive alcohol use can affect liver function, already a factor to consider.