Potential Side Effects and Drug Interactions of Eldepryl

Eldepryl (Selegiline) can cause side effects, though not everyone experiences them. Common side effects include insomnia, dizziness, nausea, and constipation. Less frequent but more serious side effects might include hallucinations, confusion, and muscle rigidity. Report any unusual symptoms to your doctor immediately.

Certain medications interact negatively with Eldepryl. Meperidine (Demerol) and other opioid pain medications can increase the risk of serotonin syndrome, a potentially life-threatening condition. Combining Eldepryl with MAOIs (other monoamine oxidase inhibitors) is strictly forbidden due to the high risk of hypertensive crisis. Discuss all medications, including over-the-counter drugs and supplements, with your doctor before starting Eldepryl.

Specific foods also warrant caution. Foods high in tyramine, such as aged cheeses, cured meats, and certain beers, should be avoided while taking Eldepryl. Tyramine interacts with the medication and can trigger a dangerous increase in blood pressure. Your doctor can provide a detailed list of foods to restrict.

Regular monitoring of your blood pressure is crucial while using Eldepryl, particularly if you’re also taking other medications or consuming tyramine-rich foods. Open communication with your healthcare provider is key to managing potential side effects and interactions safely and effectively.