Benadryl, while sometimes used to address Eustachian tube dysfunction (ETD) symptoms, carries potential side effects. Common ones include drowsiness, dry mouth, blurred vision, and constipation. These effects are usually mild and temporary, subsiding once you stop taking the medication. However, some individuals experience more severe reactions.
More Serious Side Effects
Less frequent, but more serious side effects include dizziness, rapid heartbeat, difficulty urinating, and confusion. Allergic reactions, ranging from skin rashes to serious breathing problems (anaphylaxis), are possible, though rare. If you notice any severe or unusual symptoms after taking Benadryl, discontinue use and seek immediate medical attention. This is especially important if you experience difficulty breathing or swelling of your face, lips, or throat.
Remember to always follow your doctor’s instructions and read the medication label carefully. Consider discussing alternative treatment options for ETD with your physician if you experience significant side effects from Benadryl.


