Potential Side Effects of Zofran: What to Watch For

Consult your doctor immediately if you experience severe side effects. Common side effects are generally mild and temporary, but some require attention.

Common Side Effects

Many experience headache, dizziness, or constipation. These usually subside as your body adjusts. Drink plenty of fluids and consider over-the-counter remedies for constipation, but always check with your doctor or pharmacist before using any additional medication.

Less Common, But Important Side Effects

Pay close attention for signs of allergic reaction, such as rash, itching, or swelling. Report any unusual changes in your heart rhythm or shortness of breath. Drowsiness is possible; avoid driving or operating machinery if affected. Blurred vision also warrants immediate medical attention.

Serious Side Effects: Seek Immediate Medical Help

While rare, serious side effects exist. These include serotonin syndrome (characterized by high fever, muscle rigidity, and confusion), prolonged QT interval (affecting heart rhythm), and liver problems (indicated by jaundice, dark urine, or light-colored stools).

Side Effect Action
Headache, dizziness, constipation Monitor; use over-the-counter remedies for constipation (after consulting a pharmacist); report if severe or persistent
Allergic reaction (rash, itching, swelling) Seek immediate medical attention
Heart rhythm changes, shortness of breath Seek immediate medical attention
Drowsiness, blurred vision Avoid driving or operating machinery; report to your doctor
Serotonin syndrome, prolonged QT interval, liver problems Seek immediate medical attention

When to Contact Your Doctor

Contact your healthcare provider if side effects are bothersome or don’t improve, or if you have concerns about any new symptoms.