Sildenafil, Vardenafil, and Tadalafil: A Comparison of PDE5 Inhibitors

Choose the medication that best suits your needs and discuss options with your doctor. Sildenafil, Vardenafil, and Tadalafil all treat erectile dysfunction by inhibiting phosphodiesterase type 5 (PDE5), but they differ in onset, duration, and potential side effects.

Sildenafil (Viagra) typically takes 30-60 minutes to work and lasts for about 4 hours. Common side effects include headache, flushing, and nasal congestion. It’s generally well-tolerated.

Vardenafil (Levitra) acts faster than sildenafil, often within 15-25 minutes, and maintains its effect for about 4-5 hours. Similar side effects to sildenafil are reported, but with potentially slightly higher occurrence rates.

Tadalafil (Cialis) boasts the longest duration of action, up to 36 hours, and its onset is usually within 30 minutes. It also presents with similar side effects, though they’re generally mild and infrequent.

Dosage adjustments may be necessary based on individual response and pre-existing health conditions. Always follow your physician’s instructions and consult them about potential drug interactions, particularly with nitrates or alpha-blockers.

Remember, these are general guidelines. Individual responses vary. Consult a medical professional for personalized advice and treatment.