Check the expiration date printed on the Benadryl packaging. This date indicates the manufacturer’s guarantee of full potency and safety. After this date, the medication might not be as effective.
Unopened Benadryl generally retains its potency for 2-3 years past the expiration date, provided it’s stored correctly.
Proper storage is key. Keep Benadryl in a cool, dry place away from direct sunlight and moisture. Avoid extreme temperatures. Improper storage accelerates degradation.
Once opened, use the medication within the timeframe recommended on the label. Typically, this is within a year or less. Discard any remaining medication after that.
Observe the medication’s appearance. Changes in color, texture, or odor could indicate degradation. Discard the medication if you notice any unusual changes.
Always consult your doctor or pharmacist if you have questions about using Benadryl beyond its expiration date, or if you notice anything unusual about the medication’s appearance.


