Viagra, or sildenafil, works by inhibiting an enzyme called phosphodiesterase-5 (PDE5). PDE5 breaks down cGMP, a crucial molecule in the penis. Higher cGMP levels relax the smooth muscles in blood vessels, increasing blood flow.
Increased Blood Flow and Erections
This increased blood flow is what allows for an erection. When sexually stimulated, the brain signals the release of nitric oxide, which in turn boosts cGMP production. By blocking PDE5, Viagra prolongs the effects of cGMP, leading to sustained vasodilation and improved erectile function. The dosage – 50mg or 100mg – affects the duration and intensity of this effect.
Dosage Considerations
The 50mg dose is often a starting point; 100mg may be prescribed if 50mg proves insufficient. However, higher doses don’t always guarantee better results and can increase the risk of side effects. Always follow your doctor’s recommendations regarding dosage and frequency.
