Acetazolamide is a medication that works by inhibiting carbonic anhydrase, an enzyme found in your kidneys, eyes, and brain. This inhibition reduces the reabsorption of sodium bicarbonate in the kidneys, leading to increased excretion of sodium, bicarbonate, and potassium in your urine. This process increases the acidity of your urine.
How This Affects Your Body
The resulting changes in fluid and electrolyte balance have several therapeutic effects. For instance, it reduces fluid buildup in the eyes (helpful for glaucoma), decreases intracranial pressure (useful in some forms of hydrocephalus), and helps manage altitude sickness by increasing your body’s ability to excrete excess fluid.
Specific Uses
Acetazolamide is used to treat several conditions including glaucoma, epilepsy, altitude sickness, and idiopathic intracranial hypertension. Your doctor will determine the appropriate dosage based on your specific needs and condition.
