Accutane, or isotretinoin, requires careful liver monitoring. Your doctor will likely order blood tests to check liver enzyme levels before, during, and after treatment. Elevated levels indicate potential liver damage. These tests measure alanine aminotransferase (ALT) and aspartate aminotransferase (AST).
Mild elevations in liver enzymes are sometimes observed, often resolving after treatment ends. However, significant increases necessitate immediate medical attention and may require Accutane discontinuation. Your physician will explain the specific thresholds concerning your individual case.
Pre-existing liver conditions present a higher risk. Openly discuss any prior liver issues or family history of liver disease with your dermatologist. This allows for a thorough risk assessment before starting Accutane. Regular monitoring becomes even more crucial in such cases.
Alcohol consumption can also stress the liver. While moderate drinking might not always cause problems, limiting or eliminating alcohol during Accutane therapy is highly recommended to minimize potential liver strain. Your doctor can provide personalized guidance.
Symptoms to watch for include jaundice (yellowing of the skin or eyes), dark urine, abdominal pain, and fatigue. These are red flags that require prompt medical evaluation. Don’t hesitate to contact your healthcare provider if you experience any of these.
Remember: the benefits of Accutane for severe acne must be carefully weighed against potential risks, particularly concerning liver health. Open communication with your doctor is paramount. They will guide you in managing this medication safely and effectively.


