If amoxicillin isn’t suitable, your doctor might prescribe nitrofurantoin, a commonly used alternative for uncomplicated UTIs. It’s effective against many common UTI bacteria and is often well-tolerated.
Another option is trimethoprim-sulfamethoxazole (TMP-SMX), also known as Bactrim or Septra. This antibiotic targets a wide range of bacteria, making it a versatile choice. However, increasing bacterial resistance is a concern.
For more severe UTIs or those caused by resistant bacteria, your doctor may consider fluoroquinolones like ciprofloxacin or levofloxacin. These are powerful antibiotics, but they are usually reserved for cases where other options have failed due to potential side effects.
Cephalosporins, such as cefalexin or cefpodoxime, provide another antibiotic class for UTI treatment. They offer a good alternative if you’re allergic to penicillin.
The best alternative depends on various factors, including your medical history, the severity of your infection, and the bacteria causing it. Always consult your doctor for diagnosis and treatment. Self-treating a UTI can be harmful.
| Nitrofurantoin | Macrodantin, Furadantin | Uncomplicated UTIs |
| Trimethoprim-Sulfamethoxazole (TMP-SMX) | Bactrim, Septra | Uncomplicated and some complicated UTIs |
| Ciprofloxacin | Cipro | Severe or resistant UTIs |
| Cefalexin | Keflex | Alternative if penicillin allergic |


