Cialis, or tadalafil, primarily works by inhibiting phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP). Increased cGMP levels relax blood vessels, improving blood flow. This mechanism explains its effectiveness in treating erectile dysfunction and benign prostatic hyperplasia (BPH).
Renal Effects: A Closer Look
While Cialis primarily targets the circulatory system, its impact on the kidneys is a pertinent consideration. Studies suggest a low risk of direct renal damage from Cialis. However, pre-existing kidney conditions, such as dehydration or renal impairment, might increase the risk of side effects. Individuals with these conditions should discuss Cialis use with their doctors before starting treatment. Proper hydration is recommended during Cialis use to minimize potential renal strain. Monitoring kidney function through regular blood tests, especially in individuals with pre-existing renal issues, is advisable.
Reports of renal complications associated with Cialis are rare. Nonetheless, individuals experiencing unexpected changes in urination frequency, pain, or blood in their urine should seek immediate medical attention. These symptoms are not definitively linked to Cialis, but warrant prompt medical evaluation.
