Sulfamethoxazole-trimethoprim (SMX-TMP) effectively combats various bacterial infections. This combination targets a broad spectrum of Gram-positive and Gram-negative bacteria, making it versatile for treating numerous conditions.
Urinary Tract Infections (UTIs)
SMX-TMP is a first-line treatment for uncomplicated UTIs, including cystitis and pyelonephritis. Dosage typically ranges from one to two tablets twice daily for seven to ten days. Always follow your doctor’s instructions carefully.
Respiratory Infections
The combination effectively treats acute exacerbations of chronic bronchitis and some types of pneumonia. Treatment duration varies depending on the severity and type of infection, but often lasts for seven to fourteen days. Your physician will determine the appropriate dosage.
Other Infections
Beyond UTIs and respiratory infections, SMX-TMP proves useful in managing skin and soft tissue infections, such as cellulitis and abscesses. It’s also used in treating traveler’s diarrhea caused by specific bacteria. Dosage and treatment length depend on the particular infection and its severity. Consult your healthcare provider for accurate guidance.
Important Considerations
While generally safe, SMX-TMP carries potential side effects, including allergic reactions, nausea, and digestive upset. Patients with kidney or liver problems require careful monitoring and adjusted dosages. Always inform your doctor about any allergies or medical conditions before taking SMX-TMP.


