Doxycycline is a common prophylactic medication against malaria, particularly in areas with chloroquine-resistant Plasmodium falciparum. It’s not a perfect solution, but it significantly reduces your risk.
Dosage and Administration
The recommended dosage varies depending on your travel destination and risk factors. Always consult a healthcare professional before taking any malaria medication.
- Typical adult dosage for prophylaxis: One 100mg tablet daily, starting 1-2 days before travel and continuing for 4 weeks after leaving the malaria-risk area. Alternative regimens: Some protocols use a 200mg dose twice weekly. Your doctor will determine the best schedule for your circumstances.
Take doxycycline with a full glass of water, and avoid taking it with dairy products or antacids, which can reduce absorption.
Important Considerations
- Drug interactions: Doxycycline interacts with several medications. Discuss all your current medications with your doctor before starting prophylaxis. Side effects: Common side effects include nausea, vomiting, diarrhea, and photosensitivity. Severe reactions are rare but possible. Pregnancy and breastfeeding: Doxycycline is generally avoided during pregnancy and breastfeeding due to potential risks to the developing fetus or infant. Alternatives should be discussed with your healthcare provider. Not a guarantee: While doxycycline greatly reduces your risk, it does not provide 100% protection against malaria. You should still take precautions to avoid mosquito bites.
Alternatives to Doxycycline
Other malaria prophylaxis medications are available, such as mefloquine, atovaquone-proguanil, and primaquine. Your doctor will help you choose the most appropriate option based on your individual needs and travel plans. Discuss these options thoroughly for a personalized approach to malaria prevention.


