Doxycycline can interact with several medications, potentially altering their effectiveness or increasing the risk of side effects. Always inform your doctor about all medications, supplements, and herbal remedies you’re taking before starting doxycycline.
Antacids containing calcium, magnesium, aluminum, or iron reduce doxycycline absorption. Separate your doxycycline intake from these antacids by at least two hours.
Warfarin (Coumadin) and other anticoagulants may have their effects enhanced by doxycycline, leading to increased bleeding risk. Close monitoring of your blood clotting time is necessary if you’re on both medications.
Methotrexate’s toxicity can be increased by doxycycline. Your doctor needs to closely monitor you if you’re taking both.
Oral contraceptives may have reduced effectiveness when taken concurrently with doxycycline. Consider using a backup contraceptive method.
Doxycycline can increase the effects of theophylline, potentially leading to elevated levels and side effects. Regular theophylline level checks are recommended.
Some seizure medications may have altered effects when taken with doxycycline. Discuss any seizure medications with your physician.
Dairy products and calcium-rich foods can also interfere with doxycycline absorption. Avoid consuming these with your medication.
This information is not exhaustive. Consult your doctor or pharmacist for a complete list of potential drug interactions specific to your situation.
