Begin by establishing a clear diagnosis. Prednisone’s potent anti-inflammatory effects treat various conditions, but precise diagnosis guides dosage and duration. Confirm the indication with thorough history-taking and relevant investigations. Consider alternatives if possible; Prednisone carries significant risks.
Next, carefully determine the appropriate dose. Start with the lowest effective dose, individualizing it based on patient factors like weight, age, and disease severity. For instance, a typical starting dose for inflammatory conditions could be 20-40mg daily, adjusted depending on the response. Closely monitor for side effects; this is paramount.
Then, establish a tapering schedule. Avoid abrupt cessation to prevent adrenal insufficiency. Reduce the daily dose gradually–typically by 5-10mg every few days–over several weeks or months. The duration depends on the condition and patient response. This gradual reduction minimizes withdrawal symptoms.
Finally, emphasize patient education and monitoring. Inform patients about potential side effects, such as weight gain, mood changes, and increased blood sugar. Regular follow-up appointments for blood tests and clinical evaluations are critical to assess efficacy and adjust the dosage or treatment plan accordingly. Always prioritize patient safety.


