Begin labetalol infusion at 0.5 mg/minute. This rate should be easily managed by most infusion pumps.
Monitoring Blood Pressure
Closely monitor blood pressure every 2-5 minutes during the initial titration phase. Adjust the infusion rate based on the patient’s response. Aim for a gradual reduction in blood pressure, avoiding abrupt drops.
Adjusting the Infusion Rate
Increase the infusion rate by 0.5 mg/minute increments every 10-20 minutes as needed. This allows for careful observation of the patient’s response and minimizes the risk of hypotension. The maximum infusion rate is generally 2 mg/minute; however, individual patient needs and the severity of their hypertension will influence this.
Maximum Daily Dose
Remember to consult the latest prescribing information for your region. The maximum daily dose of labetalol varies. Always prioritize patient safety and closely monitor for adverse effects. Contact your prescribing physician for guidance exceeding standard protocols.


