Always inform your doctor or pharmacist about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies, before starting amoxicillin. This includes vitamins and even seemingly harmless products.
Oral contraceptives: Amoxicillin may reduce the effectiveness of some birth control pills. Consider using a backup method of contraception while taking amoxicillin and for a short period afterward. Consult your doctor for specific advice.
Methotrexate: Combining amoxicillin with methotrexate can increase the risk of methotrexate toxicity. Your doctor may need to monitor your blood counts more closely.
Warfarin: Amoxicillin can affect how your body processes warfarin, a blood thinner. Regular blood tests are necessary to adjust your warfarin dosage appropriately while taking amoxicillin.
Allopurinol: Concurrent use of amoxicillin and allopurinol can increase the chance of skin reactions. Report any skin rashes or unusual symptoms immediately.
Probenecid: Probenecid reduces the kidney’s elimination of amoxicillin, potentially increasing the risk of side effects. Your doctor may adjust your amoxicillin dosage accordingly.
This information is not exhaustive. Many other drug interactions are possible. Always seek professional medical advice regarding potential drug interactions before combining amoxicillin with other medications.


