Always inform your doctor about all medications you’re taking, including over-the-counter drugs, supplements, and herbal remedies, before starting tadalafil. This is crucial for preventing potentially harmful interactions.
Nitrates: Combining tadalafil with nitrates (found in medications for chest pain) can cause a dangerous drop in blood pressure. Avoid this combination.
Alpha-blockers: Tadalafil may enhance the blood pressure-lowering effects of alpha-blockers (used to treat high blood pressure and enlarged prostate). Your doctor might adjust your dosages.
CYP3A4 inhibitors: Medications that inhibit the CYP3A4 enzyme (like ketoconazole and ritonavir) can increase tadalafil levels in your blood, potentially leading to side effects. Your doctor may recommend a lower tadalafil dose.
Other medications: Certain antifungals, antibiotics, and HIV medications can interact with tadalafil. Discuss all your medications with your doctor to assess potential interactions and ensure your safety.
Grapefruit juice: Avoid grapefruit juice while taking tadalafil, as it can increase its levels in your blood and boost the risk of side effects.
Alcohol: While moderate alcohol consumption usually doesn’t significantly interact with tadalafil, excessive alcohol can worsen potential side effects. Consume alcohol responsibly.
This information is not exhaustive. Consult your physician or pharmacist for personalized advice.
