Monitoring for Adverse Effects and Treatment Adjustments

Closely monitor neonates receiving sildenafil for hypotension, which may manifest as decreased blood pressure and changes in heart rate. Regularly assess oxygen saturation and respiratory rate. Observe for any signs of cyanosis or respiratory distress.

Monitor for gastrointestinal effects such as vomiting or diarrhea. These symptoms should be documented and their severity assessed. Adjustments to the dosage or treatment plan might be necessary depending on the severity and response to therapy.

Regularly check for visual disturbances, including changes in vision acuity or color perception. Document any reported visual changes. Consider ophthalmological consultation if significant visual impairment is noted.

Blood pressure, heart rate, and oxygen saturation should be measured frequently, ideally continuously in high-risk patients. These parameters are crucial for timely detection of adverse effects and subsequent dose adjustments.

Dose adjustments should be guided by clinical response and careful monitoring of adverse effects. Reduce the dosage if adverse effects occur and escalate treatment if the desired effect is not achieved. Consult with a neonatologist or pediatric cardiologist for dosage guidance, especially in complex cases.

Detailed records of medication administration, observed adverse effects, and treatment modifications are paramount for effective management and future reference. This information allows for appropriate evaluation of treatment efficacy and potential risks in subsequent treatments.