Your doctor will consider several factors when deciding between doxycycline and minocycline for your rosacea. These choices are personalized!
Prior Antibiotic Use and Allergies
- A history of successful treatment with one of these antibiotics strongly suggests using it again. Known allergies to tetracyclines eliminate that option. Always disclose all allergies.
Gastrointestinal Tolerance
Minocycline can cause more gastrointestinal upset than doxycycline. If you have a sensitive stomach, doxycycline might be a better choice. Consider discussing this with your doctor.
Pregnancy and Breastfeeding
- Both medications carry potential risks during pregnancy and breastfeeding. Discuss your situation thoroughly with your doctor to weigh the benefits against the potential risks. Alternatives may be explored during these periods.
Other Medications
Interactions with other medications you are taking will factor into the choice. Provide your doctor with a complete medication list.
Cost and Insurance Coverage
Doxycycline is typically less expensive than minocycline. Insurance coverage can vary significantly, so check your plan’s formulary.
Individual Response
Treatment response is unique. What works well for one person may not work as well for another. Monitoring your progress and adjusting the treatment plan as needed is important.
Liver Function
Minocycline can affect liver function in rare cases, this should be considered for patients with existing liver issues.


