Generic Actos (pioglitazone) carries the same risk of side effects as brand-name Actos. Monitor yourself for these potential issues.
Common Side Effects
Many experience fluid retention (weight gain, swelling in ankles or legs), headache, and upper respiratory infections. Less common, but still possible, are increased appetite and abnormal liver function tests. Report any persistent or worsening symptoms to your doctor.
Serious Side Effects
While rare, serious side effects exist. These include heart failure, bladder cancer, and bone fractures. Consult your doctor immediately if you experience unusual shortness of breath, persistent lower back pain, or unexplained bone pain.
Drug Interactions
Certain medications can interact negatively with pioglitazone. This interaction can increase the risk of side effects or reduce the effectiveness of either drug. Carefully review your medications with your physician or pharmacist, noting the following significant interactions:
| Insulin and other diabetes medications | Increased risk of hypoglycemia (low blood sugar) |
| Certain heart medications (e. g., some diuretics) | Increased risk of fluid retention |
| CYP3A4 inhibitors (e. g., ketoconazole) | Increased blood levels of pioglitazone, raising the risk of side effects |
| CYP3A4 inducers (e. g., rifampin) | Decreased blood levels of pioglitazone, reducing effectiveness |
Before Taking Generic Actos
Discuss your complete medical history with your doctor, including any pre-existing conditions, such as heart disease, liver problems, or a history of bladder cancer. This thorough assessment helps minimize risks.
Monitoring Your Health
Regular check-ups are crucial to monitor your blood sugar levels, liver function, and overall health while using pioglitazone. Don’t hesitate to contact your doctor if you have concerns.
