Tretinoin, while effective, can cause skin irritation. Expect dryness, redness, peeling, and burning. These usually lessen with continued use and adjusting application frequency. Start with infrequent application, perhaps every other night.
Sun sensitivity is a significant concern. Always use a broad-spectrum sunscreen with an SPF of 30 or higher daily, even on cloudy days. Avoid prolonged sun exposure.
Some experience increased acne breakouts initially. This is often temporary, a purging phase as tretinoin accelerates cell turnover. Persist with treatment; results typically improve over time.
Rare but possible side effects include hyperpigmentation (dark spots) in individuals with darker skin tones. Precise application and diligent sun protection mitigate this risk.
Interactions: Tretinoin can interact with certain medications and products. Avoid using harsh scrubs, strong chemical exfoliants (like AHAs/BHAs), or other retinoids concurrently. Inform your doctor about all medications and skincare products you are using, particularly antibiotics and benzoyl peroxide, to prevent unexpected reactions.
If you notice unusual reactions, such as severe skin irritation or persistent discomfort, discontinue use and consult a dermatologist immediately. They can guide you on appropriate management and alternative treatments.


