Glipizide and metformin, while effective in managing type 2 diabetes, can cause side effects. Hypoglycemia (low blood sugar) is a common concern with glipizide. Symptoms include shakiness, sweating, dizziness, and confusion. Carry glucose tablets or a sugary drink to quickly raise your blood sugar if you experience these symptoms. Regular blood glucose monitoring is crucial for early detection and management of hypoglycemia.
Gastrointestinal Issues
Metformin frequently causes gastrointestinal upset, including nausea, diarrhea, and vomiting. These side effects usually lessen over time. Consider taking metformin with food to minimize discomfort. Severe or persistent gastrointestinal problems require medical attention.
Rare but serious side effects include lactic acidosis (a build-up of lactic acid in the blood), primarily with metformin. Risk factors include kidney disease, liver disease, and excessive alcohol consumption. Immediately seek medical help if you experience muscle weakness, unusual fatigue, or difficulty breathing. Your doctor should monitor your kidney function regularly while you’re on metformin.
Other potential side effects include allergic reactions (rash, itching, swelling), vitamin B12 deficiency (with long-term metformin use), and weight gain. Open communication with your doctor regarding any new or worsening symptoms is paramount for safe and effective diabetes management. They can adjust your medication or recommend other strategies to mitigate side effects.
