Isotretinoin can affect appetite, sometimes leading to weight loss or gain. Changes in body composition are a possibility, not a certainty. While some experience decreased appetite resulting in weight reduction, others report increased appetite and subsequent weight gain.
Changes in Lipid Profiles
Increased cholesterol and triglyceride levels are frequently reported side effects of isotretinoin. These changes in lipid profiles, often requiring monitoring with blood tests, can indirectly contribute to weight fluctuations. Your doctor will monitor your lipid levels and advise you on dietary adjustments if necessary.
Gastrointestinal Issues
Nausea and vomiting are common early side effects. These digestive problems can hinder food intake, possibly leading to unintended weight loss. Mild nausea can often be managed with smaller, more frequent meals. More significant gastrointestinal distress requires medical attention.
Dryness and Mouth Sores
Isotretinoin causes dryness in many patients, affecting the mouth, lips, and skin. This dryness can make eating uncomfortable, potentially reducing food consumption and contributing to weight changes. Adequate hydration and lip balm are key in mitigating this side effect.
