Entocort (budesonide) generally causes fewer systemic side effects than prednisone because it’s a corticosteroid with more localized action in the gut. Prednisone, being a systemic corticosteroid, affects the entire body.
Common side effects of prednisone include weight gain, increased appetite, fluid retention, mood changes (irritability, anxiety, depression), insomnia, high blood pressure, increased blood sugar, and thinning of the bones (osteoporosis). Serious, though less common, side effects can include infections, cataracts, glaucoma, and increased risk of developing stomach ulcers.
Entocort side effects are usually milder and often gastrointestinal in nature. These can include nausea, abdominal pain, and headache. The risk of serious side effects is considerably lower compared to prednisone.
While both medications can cause increased risk of infection, this risk is significantly higher with prednisone due to its widespread immunosuppressive effects. Your doctor will carefully consider your individual risk factors and health status when determining the best treatment option for you.
Remember, this information is not a substitute for professional medical advice. Discuss the potential benefits and risks of each medication with your doctor to make an informed decision about your Crohn’s disease management.
