Domperidone primarily works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) and the gastrointestinal tract. This blockage prevents dopamine from triggering nausea and vomiting. Simultaneously, it stimulates the release of acetylcholine, enhancing gastric motility and speeding up the emptying of your stomach. This dual action makes it effective for treating various conditions.
Treating Nausea and Vomiting
Domperidone effectively relieves nausea and vomiting caused by various factors, including gastroparesis (delayed stomach emptying), chemotherapy, and post-operative nausea. It’s particularly beneficial for those experiencing nausea and vomiting without significant gastrointestinal pain. Doctors consider this medication safe for short-term use in these cases.
Improving Gastric Motility
For individuals with functional dyspepsia (indigestion) or gastroparesis, Domperidone helps improve the movement of food through the digestive system. By accelerating stomach emptying, it can alleviate symptoms such as bloating, fullness, and heartburn. It is crucial to remember that this medicine is only part of a comprehensive treatment plan for these conditions.
Important Considerations
While generally safe for short-term use, potential side effects like headache, diarrhea, or galactorrhea (abnormal milk production) might occur. Always consult your doctor before starting any medication, including Domperidone, especially if you have underlying heart conditions, are breastfeeding, or taking other medications. They will carefully assess your individual needs and advise on the appropriate dosage and duration of treatment.
