Finasteride combats androgenetic alopecia by specifically inhibiting the enzyme 5α-reductase.
This enzyme converts testosterone into dihydrotestosterone (DHT), a potent androgen significantly contributing to hair follicle miniaturization–the hallmark of male pattern baldness. By blocking 5α-reductase, finasteride reduces DHT levels in the scalp.
- This reduction slows, and in some cases stops, further hair loss. Importantly, it’s type II 5α-reductase that finasteride primarily targets; this isoenzyme is predominantly found in hair follicles.
Consequently, the hair follicles receive less DHT, allowing them to maintain a healthier size and continue producing hair. Note that finasteride does not regrow already lost hair; its primary action is to prevent further miniaturization and potential loss.
The impact varies among individuals due to factors like genetics, age, and severity of hair loss. Results typically manifest gradually, often becoming noticeable after several months of consistent use. Maintenance therapy is generally required to sustain the benefits.
Remember to consult a healthcare professional before initiating finasteride treatment. They can assess your suitability for the medication and discuss potential side effects and alternatives.
