Synthroid tablets contain levothyroxine sodium, the active ingredient. The tablet’s composition also includes inactive ingredients that help bind the medication and ensure consistent dosage. These inactive ingredients vary slightly depending on the tablet strength. Do not assume all Synthroid tablets are identical in composition.
Tablet Scoring
Many Synthroid tablets feature a score line, allowing for potential splitting. However, this score line isn’t always present, and its presence doesn’t guarantee accurate dosage division.
- Accuracy: Splitting scored tablets might not result in two perfectly equal halves. Dosage inaccuracy could impact treatment effectiveness. Consistency: The consistency of the split depends on the tablet’s age, storage conditions, and the method used to split it. Older or damaged tablets are more likely to break unevenly. Manufacturer Recommendations: Always check your specific Synthroid prescription information. The manufacturer’s instructions should clearly state whether splitting is acceptable for your prescribed dosage.
Alternative Dosage Options
If precise dosage adjustment is necessary, discuss alternative dosage options with your doctor. They might prescribe a different formulation or strength of levothyroxine to achieve the desired therapeutic level without the need for splitting tablets.
Lower dosage tablets: Switching to a lower strength tablet may eliminate the need for splitting. Liquid formulations: In some cases, liquid levothyroxine offers more precise dosage control.
Always consult your physician before altering your medication regimen or attempting to split tablets.


